Prompted by: Alzheimer’s Association International Conference
I wonder throughout all of the conference events (apparently designed to tune worldwide efforts against AD — Alzheimer’s disease), is anyone there talking about cannabis being the only drug scientifically mentioned (and easily safely available) to actually oppose AD?
Based upon personal interactions with Alzheimer’s Association, RSS feeds, etc., I assume the stress managing (and bodily tuning) plant scientifically called cannabis remains absent there — and that’s a terribly serious problem (causing ample suffering) that Stress Health serves to address as a novel entertainment layer (leveraging the power of the Internet to entertain for interest — so public focus) for the cause.
Being a personal caregiver of someone with that deadly disease, I boldly support their efforts to find a cure (even if by effective non-cannabis means), but medical cannabis has been lawfully (at the state level) applied here already with astonishing results.
The following highlights come from an article spelling it all out.
More than five million Americans have Alzheimer’s today. One in three seniors will die with Alzheimer’s or another dementia, and Alzheimer’s is the sixth leading cause of death in the nation, costing America about $203 billion in 2013.
Chuanhai Cao and other researchers at the University of South Florida and Thomas Jefferson University wanted to investigate the “potential therapeutic qualities of Δ9-tetrahydrocannabinol (THC) with respect to slowing or halting the hallmark characteristics of Alzheimer’s disease.”
So they treated Alzheimer’s research cells (N2a-variant amyloid-β protein precursor (AβPP) cells) with THC and examined them for amyloid-β at the 6, 24, and 48-hour time markers. Amyloid-β is a type of protein that is linked to Alzheimer’s symptoms. The researchers found THC “to be effective at lowering Aβ levels … in a dose-dependent manner.”
The main active ingredient in pot “directly interacts” with amyloid-β, “thereby inhibiting aggression”. THC was also effective at lowering other key Alzheimer’s Disease markers. Furthermore “no toxicity” was observed from the THC. The researchers also found THC “enhances” the function of the cell’s energy factories — the mitochondria.
“THC is known to be a potent antioxidant with neuroprotective properties, but this is the first report that the compound directly affects Alzheimer’s pathology by decreasing amyloid beta levels, inhibiting its aggregation, and enhancing mitochondrial function,” stated study lead author Chuanhai Cao, PhD and a neuroscientist at the Byrd Alzheimer’s Institute and the USF College of Pharmacy.
Other research in the same journal that month indicates THC boosts the body’s natural anti-Alzheimer’s fighting mechanism — the endocannabinoid system.
Alzheimer’s Disease is thought to result from a lifetime of brain inflammation. Cannabis is one of the most safe anti-inflammatories in medicine. Some neuroscientists believe a bout of pot smoking in early adulthood may prevent Alzheimer’s onset later in life. Cannabis slows brain aging, Time reported in 2012.
Smoking, vaping, or eating the pot molecules THC and CBD directly effects nerve cell function, reducing chronic brain inflammation, oxidative stress, and cellular dysfunction — all the while promoting stability of the human body’s internal environment (homeostasis) and healthy brain cells (neurotrophic support), studies show.
“What we found was that not only did the single puff a day reverse the memory impairment but also restarted neurogenesis,” Ohio State University, Gary Wenk told the Seattle Post Intelligencer this year.
Other studies have shown THC inhibits other key pathological markers of Alzheimer’s Disease.
I wrote much more on this subject at the core of Stress Health’s Mind Always Matters campaign (specifically, the Heads Up program).
If you know anyone with AD, it’s critical that you consider the information provided here (including the Heads Up program).
It’s nothing shy of a global outrage to allow millions of people to suffer due to the sometimes lingering (and otherwise continuing) effects of a plant being horribly unethically demonized for several decades and excessively counting.